俄亥俄州立大學(xué)在哥倫布的主校區(qū)共有19個學(xué)院、170個科（系）、超過10500門課程可供選擇。大學(xué)的學(xué)期制度原本采用“學(xué)季”（Quarter）制，但從2012年秋季開始已改為學(xué)期（Semester）制。

大學(xué)設(shè)置有以下學(xué)院：

1、College of Dentistry

2、College of Education

－School of Educational Policy and Leadership

－School of Physical Activity and Educational Services

－School of Teaching and Learning

3、College of Engineering

－Austin E. Knowlton School of Architecture

4、College of Food, Agricultural, and Environmental Sciences

－Agricultural Technical Institute

5、School of Natural Resources

6、College of Human Ecology

7、College of Medicine and Public Health

－School of Allied Medical Professions

－School of Biomedical Science

－School of Public Health

8、College of Nursing

9、College of Optometry

10、College of Pharmacy

11、College of Social Work

12、College of Veterinary Medicine

13、Colleges of the Arts and Sciences

－College of the Arts

－School of Music

－College of Biological Sciences

College of Mathematical and Physical Sciences

－College of Social and Behavioral Sciences

－School of Journalism and Communication

14、Graduate School

15、Max M. Fisher College of Business

16、Michael E.Moritz College of Law

17. John Glenn College Of Public Affair

分校校區(qū)：

1.The Ohio State University （Lima Campus）

2.The Ohio State University （Mansfield Campus）

3.The Ohio State University （Marion Campus）

－Delaware Center

4.The Ohio State University （Newark Campus）